Gerd 6l492c

Gastroesophageal Reflux Disease Jasmine Aratea

INTRODUCTION

GERD cases recorded in Amang Rodriguez Medical Center Year

Gerd Cases Reported

2010

5

2011

1

2012

3

2013

1

GERD cases recorded in Jose Reyes Memorial Medical Center Year

Gerd Cases Reported

2011

7

2012

3

2013

5

Age Range

Cases Reported

0-10

2

11-20

3

21-40

4

41-60

2

61-80

3

Sex

Cases Reported

Female

4

Male

11

• In a survey study based on the US Census Bureau, Population Estimates and International Data Base (2004), statistics shows that the highest grossing extrapolation prevalence rate of GERD was recorded in China with almost 38,965,428 cases reported. Second in line is India with 31, 952, 118 cases reported. In the Philippines, almost 2, 587, 250 GERD cases were recorded in 2004 which is almost 3% of today’s population. Today, numerous studies are promoted by health research centers to increase the fight for curing the GERD disease.

PATHOGENESIS OF GERD Mafe Cabiles

Gastric Acid Production

Among the mechanisms thought to contribute to the development of GERD are • Decreased LES resting tone – the normal LES pressure must be higher than the gastric pressure

• Impaired Esophageal Acid Clearance • Delayed Gastric Emptying or Gastro Paresis • Decreased Salivation • Impaired Tissue Resistance

Pathological VS. Normal Bea Antonio

Normal Esophagus • Covered with non-keratinized squamous epithelium

Barrett’s Esophagus • The squamous epithelium is replaced with goblet cells, called intestinal metaplasia. • Columnar Epithelia • Major risk factor of GERD • About 1 out of 10 patients with GERD are found to have Barrett’s Esophagus.

Alyzza Khimberly Vergara

• Heart burn and acid regurgitation • Dysphagia and Odynophagia • Non-cardiac chest pain • Extraesophageal symptoms • Symptom relapse and chronicity

• Antacids that neutralize stomach acid • Prescription-strength medications • Surgery and other procedures used if medications don't help.

Bianca Dela Cruz

Conclusion: • The pathophysiology of GERD is clearly multifactorial, despite the many medical intervention available in the medical field does not in any way alleviate this disease entirely. • Successful treatment of GERD in patients whose symptoms are poorly controlled with medical treatment remains a challenge. GERD remains a significant clinical problem. A number of major questions remain unstudied or, as yet, unanswered.

References • Esophagus: Barrett's esophagus, dysplasia and adenocarcinoma. (n.d.). Retrieved from http://atlasgeneticsoncology.org/Tumors/BarrettsEsophagID5591.html • Barrett's Esophagus - National Digestive Diseases Information Clearinghouse. (n.d.). Retrieved from http://digestive.niddk.nih.gov/ddiseases/pubs/barretts/ • Ways to Increase Stomach Acid Production [Video file]. (n.d.). Retrieved from http://www.branchbasics.com/learn/ways-to-increase-stomach-acidproduction/ • Acid Production in stomach_1.flv [Video file]. (n.d.). Retrieved from http://www.youtube.com/watch?v=Wvpz9m92ZQA • Developments in pathogenesis and diagnosis of gastroesophageal reflux disease [Video file]. (n.d.). Retrieved from http://cat.inist.fr/?aModele=afficheN&sidt=18800524 • [Video file]Retrieved from http://www.cedrugstorenews.com/app//lessons/page_view_ui.cfm?l essonuid=&pageid=20E9006810884CADCC67B1249653D55F